Antimalarial Drug Resistance and Implications for the WHO Global Technical Strategy
نویسندگان
چکیده
منابع مشابه
Antimalarial drug resistance
Antimalarial drug resistance is of great concern in the WHO South-East Asia (SEA) Region. A high degree of resistance of Plasmodium falciparum to chloroquine and sulfadoxine-pyrimethamine is prevalent in this Region. Multidrug resistance is prevalent in some parts of the Greater Mekong Sub-region. Artemisinin and its derivatives in combination with other effective partner drugs, which showed fa...
متن کاملAntimalarial drug resistance.
Malaria, the most prevalent and most pernicious parasitic disease of humans, is estimated to kill between one and two million people, mainly children, each year. Resistance has emerged to all classes of antimalarial drugs except the artemisinins and is responsible for a recent increase in malaria-related mortality, particularly in Africa. The de novo emergence of resistance can be prevented by ...
متن کاملAntimalarial Drug Resistance
Malaria is a hematoprotozoan parasitic infection transmitted by certain species of anopheline mosquitoes. Four species of Plasmodium commonly infect humans, but Plasmodium falciparum, accounts for the majority of instances of morbidity and mortality. There has been a resurgence of interest in malaria in recent years because the efforts at control have foundered after the failure of the global e...
متن کاملWHO Global Strategy for Containment of Antimicrobial Resistance
Acknowledgements The World Health Organization (WHO) wishes to acknowledge with gratitude the significant support from the United States Agency for International Development (USAID) and additional assistance for this work from the United Kingdom Department for International Development and the Ministry of Health, Labour and Welfare, Japan. This strategy is the product of collaborative efforts a...
متن کاملA mathematical model for antimalarial drug resistance.
We formulate and analyze a mathematical model for malaria with treatment and the well-known three levels of resistance in humans. The model incorporates both sensitive and resistant strains of the parasites. Analytical results reveal that the model exhibits the phenomenon of backward bifurcation (co-existence of a stable disease-free equilibrium with a stable endemic equilibrium), an epidemiolo...
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ژورنال
عنوان ژورنال: Current Epidemiology Reports
سال: 2021
ISSN: 2196-2995
DOI: 10.1007/s40471-021-00266-5